Unsubstituted Phenols
Apexbio Technology LLC Edrophonium (chloride),250mg CAS# 116-38-1
Edrophonium is a competitive inhibitor of acetylcholinesterase (AChE) [1]. AChE is an extrinsic membrane-hound enzyme that functions in the central and peripheral nervous systems. AChE rapidly terminates the ACh receptor-mediated signal transmission by hydrolyzing Ach. Inhibition of AChE results in accumulation of ACh in the synaptic cleft and leads to impeded neurotransmission [2].In vitro: Edrophonium inhibited AChE activity in human red blood cells, purified calf forebrain, and octopus brain with Ki values of 0.2, 0.2, and 0.4 μM, respectively. The IC50s were 0.2, 0.05, and 0.5 μM, respectively [1]. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC HY-W013372 50mg Medchemexpress, 7,8-Dihydroxyflavone CAS:38183-03-8 Purity:>98%
Medchemexpress, HY-W013372 50mg 7,8-Dihydroxyflavone CAS:38183-03-8 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W015326 100mg Medchemexpress, 3-Hydroxymandelic Acid CAS:17119-15-2 Purity:>98%
Medchemexpress, HY-W015326 100mg 3-Hydroxymandelic Acid CAS:17119-15-2 3-Hydroxymandelic Acid, a metabolite of Phenylephrine , Phenylephrine is a α-receptor agonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![eMolecules Medchem Express / Droxidopa / 5mg / 506404011 / HY-13458 / / 23651-95-8 / [null] / 213.189 / C9H11NO5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448942.PNG-250.jpg)
eMolecules Medchem Express / Droxidopa / 5mg / 506404011 / HY-13458 / / 23651-95-8 / [null] / 213.189 / C9H11NO5
Medchem Express / Droxidopa / 5mg / 506404011 / HY-13458 / / 23651-95-8 / [null] / 213.189 / C9H11NO5
eMolecules Medchem Express / Etamivan / 100mg / 446273625 / HY-B1096 / / 304-84-7 / MFCD00026727 / 223.272 / C12H17NO3
Medchem Express / Etamivan / 100mg / 446273625 / HY-B1096 / / 304-84-7 / MFCD00026727 / 223.272 / C12H17NO3
Apexbio Technology LLC Carbidopa 28860-95-9 25mg
Carbidopa (CAS 28860-95-9) is a peripheral aromatic L-amino acid decarboxylase inhibitor that limits the peripheral conversion of levodopa to dopamine thereby increasing the availability of levodopa for transport into the central nervous system In addition to its established role in Parkinson s disease mechanism studies Carbidopa has been identified as a selective modulator of the aryl hydrocarbon receptor (AhR) influencing downstream signaling pathways Recent studies indicate its potential to suppress the proliferation of pancreatic cancer cells and inhibit tumor growth supporting its use in investigations related to tumor biology and anticancer pharmacology
Apexbio Technology LLC MIM1 509102-00-5 10mg
MIM1 (CAS 509102-00-5) is a selective small molecule inhibitor targeting the BH3-binding groove of MCL-1 an anti-apoptotic BCL-2 family protein By binding competitively to MCL-1 MIM1 disrupts its interaction with pro-apoptotic BH3-only proteins thereby neutralizing MCL-1-mediated inhibition of apoptosis In biochemical assays MIM1 displayed IC50 values of 4 7 4 8 M for competing with FITC-MCL-1 SAHBA and FITC-BID BH3 peptides In cellular models of B-ALL MIM1 induced caspase activation and cell death specifically in MCL-1-dependent cells with minimal effects on BCL-XL-dependent counterparts MIM1 is valuable for investigating the role of MCL-1 in apoptosis and for evaluating therapeutic strategies in MCL-1-driven malignancies
Apexbio Technology LLC Deoxyarbutin 53936-56-4 50mg
Deoxyarbutin (CAS 53936-56-4) is a small molecule that acts as a reversible inhibitor of tyrosinase a key enzyme involved in melanin biosynthesis By targeting tyrosinase Deoxyarbutin effectively suppresses enzymatic activity exhibiting an IC50 value of 50 nM in inhibition assays This compound is widely utilized in biomedical research to study melanogenesis explore regulatory mechanisms of skin pigmentation and evaluate potential therapeutic approaches for pigmentary disorders
eMolecules Shikonin | 517-89-5 | MFCD00075680 | 100mg
Apollo Scientific | Shikonin | 100mg | 562460577 | BISN0323 | | 517-89-5 | MFCD00075680 | 288.299 | C16H16O5
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Apexbio Technology LLC Salidroside 10338-51-9 20mg
Salidroside (CAS 10338-51-9) is a naturally occurring phenylpropanoid glycoside isolated primarily from Rhodiola species It exerts multiple biological effects through modulation of cellular pathways related to oxidative stress inflammation and apoptosis including activation of the PI3K/Akt signaling pathway and inhibition of pro-inflammatory mediators Salidroside has been shown to protect cells from oxidative damage modulate mitochondrial function and suppress inflammatory responses in various in vitro and in vivo models This compound is widely utilized in biomedical research investigating neuroprotection cardioprotection and potential therapeutic strategies targeting metabolic and neurodegenerative disorders